SEDATIVE DRUGS FOR PAIN RELIEF – BEST OPTIONS & RECOMMENDATIONS

2. Histamine Receptor Antagonism: Some sedatives, for example antihistamines, exert their sedative effects by blocking histamine receptors in the Mind, especially H1 receptors. Histamine performs a job in wakefulness and arousal, so blocking its effects encourages sedation and sleepiness.Barbiturates are another class of sedatives, nevertheless The